Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Potassium (elemental) (from 619 mg Potassium Gluconate)
99 mg
2%
Top Medical Research Studies
9
We explored the potential of ICA-105574, an HERG activator, to combat severe mutations that cause long QT syndrome type 2 (LQT2). Using both animal models and cellular simulations, we found that ICA-105574 effectively shortened QT intervals and restored critical potassium currents in cellular models with specific HERG mutations. Our results indicate that compounds like ICA-105574 could be valuable in treating LQT2, and that advanced simulations can aid in designing future HERG activators.
Read More
9
We explored the effects of activating M-type potassium channels in the left stellate ganglion to reduce heart issues caused by acute myocardial ischemia in beagles.
After treating some dogs with retigabine before inducing ischemia, we found that this activation significantly lowered sympathetic overactivity and cardiac irregularities.
The treated group showed increased resistance to dangerous arrhythmias and better heart rhythm stability compared to those who received a placebo. Overall, targeting these potassium channels might offer a new way to manage heart arrhythmias linked to ischemia.
After treating some dogs with retigabine before inducing ischemia, we found that this activation significantly lowered sympathetic overactivity and cardiac irregularities.
The treated group showed increased resistance to dangerous arrhythmias and better heart rhythm stability compared to those who received a placebo. Overall, targeting these potassium channels might offer a new way to manage heart arrhythmias linked to ischemia.
Read More
8
We investigated the potential of a new treatment approach targeting the hERG1 potassium channel, which plays a vital role in heart rhythm regulation. By using a specialized antibody designed to disrupt the hERG1 PAS domain, we tested its ability to reduce arrhythmias in heart cells derived from a patient with Jervell and Lange-Nielsen syndrome, a severe form of long QT syndrome. Our findings showed that this treatment increased the repolarizing current and decreased the occurrence of dangerous heart electrical disturbances. This approach may pave the way for new therapies for heart rhythm disorders.
Read More
Most Useful Reviews
9
Balance of electrolytes
5 people found this helpful
I use potassium supplements alongside Magnesium Citrate to manage my high morning blood pressure effectively. It's crucial to consume them on an empty stomach before antihypertensive medication. This practice has significantly reduced swelling, which correlates with fewer pressure surges. My mother’s tachycardia improved at the age of 73. Maintaining a proper balance of electrolytes like potassium is essential for health.
Read More
7.5
Improves muscle function
Potassium gluconate effectively supports potassium levels and is essential for heart, muscle, and nervous system function. Following its introduction, I've experienced enhanced well-being, reduced muscle spasms, and improved overall health, especially during physical activity.
Read More
6
Less swelling noted
7 people found this helpful
I take potassium to support my heart muscle and alleviate cramps, pairing it with magnesium. While the convulsions remain, they have diminished. I’ve observed that taking it in the evening results in less swelling by morning, which greatly pleases me.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
- All Researches
9
We explored the potential of ICA-105574, an HERG activator, to combat severe mutations that cause long QT syndrome type 2 (LQT2). Using both animal models and cellular simulations, we found that ICA-105574 effectively shortened QT intervals and restored critical potassium currents in cellular models with specific HERG mutations. Our results indicate that compounds like ICA-105574 could be valuable in treating LQT2, and that advanced simulations can aid in designing future HERG activators.
Read More
9
We explored the effects of activating M-type potassium channels in the left stellate ganglion to reduce heart issues caused by acute myocardial ischemia in beagles.
After treating some dogs with retigabine before inducing ischemia, we found that this activation significantly lowered sympathetic overactivity and cardiac irregularities.
The treated group showed increased resistance to dangerous arrhythmias and better heart rhythm stability compared to those who received a placebo. Overall, targeting these potassium channels might offer a new way to manage heart arrhythmias linked to ischemia.
After treating some dogs with retigabine before inducing ischemia, we found that this activation significantly lowered sympathetic overactivity and cardiac irregularities.
The treated group showed increased resistance to dangerous arrhythmias and better heart rhythm stability compared to those who received a placebo. Overall, targeting these potassium channels might offer a new way to manage heart arrhythmias linked to ischemia.
Read More
8
We investigated the potential of a new treatment approach targeting the hERG1 potassium channel, which plays a vital role in heart rhythm regulation. By using a specialized antibody designed to disrupt the hERG1 PAS domain, we tested its ability to reduce arrhythmias in heart cells derived from a patient with Jervell and Lange-Nielsen syndrome, a severe form of long QT syndrome. Our findings showed that this treatment increased the repolarizing current and decreased the occurrence of dangerous heart electrical disturbances. This approach may pave the way for new therapies for heart rhythm disorders.
Read More
7
We investigated how sudden shifts in potassium levels might influence the risk of death for heart failure patients. Using a novel wavelet filtering method, our goal was to effectively monitor these short-term changes alongside existing stable potassium measurements.
With data from over 2,000 patients and more than 80,000 potassium readings, our findings underscore the importance of instability in potassium levels. While traditional models may overlook these fluctuations, our research suggests that they provide essential insights for better patient care.
With data from over 2,000 patients and more than 80,000 potassium readings, our findings underscore the importance of instability in potassium levels. While traditional models may overlook these fluctuations, our research suggests that they provide essential insights for better patient care.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Balance of electrolytes
5 people found this helpful
I use potassium supplements alongside Magnesium Citrate to manage my high morning blood pressure effectively. It's crucial to consume them on an empty stomach before antihypertensive medication. This practice has significantly reduced swelling, which correlates with fewer pressure surges. My mother’s tachycardia improved at the age of 73. Maintaining a proper balance of electrolytes like potassium is essential for health.
Read More
7.5
Improves muscle function
Potassium gluconate effectively supports potassium levels and is essential for heart, muscle, and nervous system function. Following its introduction, I've experienced enhanced well-being, reduced muscle spasms, and improved overall health, especially during physical activity.
Read More
6
Less swelling noted
7 people found this helpful
I take potassium to support my heart muscle and alleviate cramps, pairing it with magnesium. While the convulsions remain, they have diminished. I’ve observed that taking it in the evening results in less swelling by morning, which greatly pleases me.
Read More
7.5
Regulates blood pressure
4 people found this helpful
Potassium gluconate, a dietary supplement, is vital for reducing the excitability of the myocardium and enhancing intestinal activity. It's essential for nerve impulse transmission, stabilising blood pressure, and supporting various metabolic processes in the body.
Read More
9
Less heart palpitations
3 people found this helpful
This potassium supplement is perfect for replenishing minerals while on a keto diet. I experienced symptoms like dizziness and heart palpitations from a deficiency, but these vanished promptly once I began taking it.
Read More
Frequently Asked Questions
9
Less heart palpitations
3 people found this helpful
This potassium supplement is perfect for replenishing minerals while on a keto diet. I experienced symptoms like dizziness and heart palpitations from a deficiency, but these vanished promptly once I began taking it.
6
Less swelling noted
7 people found this helpful
I take potassium to support my heart muscle and alleviate cramps, pairing it with magnesium. While the convulsions remain, they have diminished. I’ve observed that taking it in the evening results in less swelling by morning, which greatly pleases me.
9
Balance of electrolytes
5 people found this helpful
I use potassium supplements alongside Magnesium Citrate to manage my high morning blood pressure effectively. It's crucial to consume them on an empty stomach before antihypertensive medication. This practice has significantly reduced swelling, which correlates with fewer pressure surges. My mother’s tachycardia improved at the age of 73. Maintaining a proper balance of electrolytes like potassium is essential for health.
7.5
Aids palpitations
Great! It has helped with my husband's heart palpitations and my leg cramps.
7.5
Improves muscle function
Potassium gluconate effectively supports potassium levels and is essential for heart, muscle, and nervous system function. Following its introduction, I've experienced enhanced well-being, reduced muscle spasms, and improved overall health, especially during physical activity.
7.5
Promotes electrolyte balance
Essential Electrolyte Support! NOW Foods' Potassium Gluconate reliably maintains electrolyte balance and promotes heart health. Each tablet offers 99 mg of potassium, aiding in muscle cramps reduction and supporting healthy blood pressure. An effective addition to my wellness routine!
7.5
Nervousness reduced
3 people found this helpful
I find this potassium gentle on the stomach and crucial for my heart and muscle health, especially after prolonged stress. I started with one tablet and increased to four throughout the day, but noticed some morning diarrhea. Listening to my body is vital, and this supplement offers a suitable dosage for everyone without the risk of overuse. My nervousness has significantly decreased with its use.
9
Supports heart health
1 people found this helpful
Potassium is an excellent aid for my heart, significantly helping with my arrhythmia. I’m very impressed and will continue to order.
References
- Kumawat A, Tavazzani E, Lentini G, Trancuccio A, Kukavica D, et al. Molecular insights into the rescue mechanism of an HERG activator against severe LQT2 mutations. J Biomed Sci. 2025;32:40. 10.1186/s12929-025-01134-w
- Peng JQ, Zhou MM, Xu L, Wang X, Tang YH, et al. Targeted M-Channel Activation in the Left Stellate Ganglion Protects Against Ischemia-Induced Ventricular Arrhythmias in Canines. J Am Heart Assoc. 2025;14:e039059. 10.1161/JAHA.124.039059
- Gregorio C, Barbati G, Scagnetto A, Lenarda AD, Ieva F. Wavelet-Mixed Landmark Survival Models for the Effect of Short-Term Changes of Potassium in Heart Failure Patients. Biom J. 2025;67:e70043. 10.1002/bimj.70043
- Ukachukwu CU, Jimenez-Vazquez EN, Salwi S, Goodrich M, Sanchez-Conde FG, et al. A PAS-targeting hERG1 activator reduces arrhythmic events in Jervell and Lange-Nielsen syndrome patient-derived hiPSC-CMs. JCI Insight. 2025;10. 10.1172/jci.insight.183444
